I use DAC:R, and i did have fps drop down to 15 - 20 before, but i figured that disabling "Use Q" and "Use E" on laneclear really boosted the fps for me, also just mess around with the settings under the laneclear tab in the script.
When there is alot going on, and huge minion waves + enemies, the fps do drop some but its still in the +20's, and a rare drop down below 20 fps.
Also i disabled alot of the drawings except E range and damage drawings.
Disabled humanizer in the injector, and absolutely all settings in the GoS (F7) tab, since the script provides all the features that you need pretty much.
Also i don't run any other scripts combined with this one.
But i would suggest that you just try out different settings and orbwalkers that suit you until you find something that works.